Old Blood, New Life
How Cleaning the Blood Became Medicine — and Where It Goes Next
By Dobri Kiprov, MD — Founder & Chief Medical Officer — and Allen P. Green, MD — Associate Medical Director, Global Apheresis.
Paperback, $18.99 — available now. 293 pages.
The Long Answer to a Short Consultation
Nearly everyone who contacts this practice arrives having read something first — a study, a headline, a three-hour podcast. They come with good questions: How much of this is actually proven? What does the trial data really say? Why does a procedure that has been performed for fifty years suddenly appear in conversations about aging?
Those questions deserve more room than a consultation gives them. Dr. Kiprov has spent more than forty years building this field — founding the American Society for Apheresis, publishing over a hundred papers that shaped the standard of care. Dr. Green is a board-certified clinical pathologist who has performed hundreds of these procedures. Between the two of us, the book is the answer we would give if there were time to give it properly.
It is not a brochure for this clinic. Its most useful pages are the ones that draw a hard line between what plasma exchange is proven to do and where its frontier indications now stand — a line that cuts against our own enthusiasm as often as it supports it. If you are weighing whether any of this is right for you, you should be able to read how the physicians proposing it actually reason about the evidence.
Nineteen Chapters, and 321 Endnotes
Every claim is sourced. Where the evidence is thin, the book says so. Each of these subjects also has a page on this site if you want the clinical version first.
Where plasma exchange is settled medicine
The autoantibody problem behind autoimmune disease, and why removing antibodies from circulation became standard care decades ago.
Autoimmune disorders at Global Apheresis →Alzheimer’s and the AMBAR trial
The largest trial of plasma exchange in Alzheimer’s disease, what its results did and did not show, and the trials now underway.
Alzheimer’s & cognitive decline →The biology of aging
Parabiosis, the dilution experiments, and the “pro-geronic” factors that accumulate in plasma over a lifetime — one of the most active frontiers in the field.
Longevity & biological age →Microplastics and “forever chemicals”
What is known about PFAS and particulate accumulation in blood, and the early work on whether plasma exchange clears any of it.
Detoxification →How the procedure actually works
What the machine does, what replacement fluid is, what a session feels like, and where the real risks are.
Therapeutic plasma exchange →Four thousand years of getting it wrong
Bloodletting, the four humors, and how an ancient intuition about the blood finally found a rigorous form.
The Physicians Who Would Treat You Here
Dobri Kiprov, MD, HP
Founder & Chief Medical Officer
A founder of the American Society for Apheresis and the first physician in the United States to earn the Hemapheresis Practitioner certification. More than a hundred peer-reviewed papers, forty years of practice, and a central role in the AMBAR trial.
Dr. Kiprov’s Full Biography →
Allen P. Green, MD
Associate Medical Director
A board-certified clinical pathologist trained at UT Southwestern, with more than five hundred plasma exchange procedures performed. He leads the affiliate program that trains physicians in this therapy nationwide.
Read a Chapter
“Bleed to Heal,” on the long era of bloodletting — it opens with the three physicians who bled George Washington to death in a single day. We will send it to you.
Reviews Are How a New Book Gets Found
This is a self-published book from two practicing physicians, not a title with a publisher’s marketing budget behind it. Its readers are essentially the whole distribution plan. If it was useful to you, a few honest sentences on Amazon do more for it than anything we can do ourselves.
Write a Review on Amazon →Questions the Book Raised?
Schedule a free discovery call and ask the authors directly whether therapeutic apheresis makes sense for your situation.
Book a Free Discovery CallOld Blood, New Life is a work of science writing for general readers. It is for informational purposes only, does not constitute medical advice, and does not describe treatment available at Global Apheresis. Applications discussed as investigational or under study are not offered here as established therapy. Consult a qualified physician to determine whether any treatment is appropriate for your situation.