Pioneers of Therapeutic
Plasma Exchange
For over four decades, we have led the science and practice of apheresis — restoring health, slowing neurological decline, and helping patients reclaim their vitality.
A Proven Approach to
Restoring Health
Therapeutic plasma exchange removes harmful antibodies, inflammatory proteins, and toxins from your blood — replacing your plasma with clean albumin solution. The result is a measurable reduction in the biological burden your body carries, unlocking your immune system's ability to heal.
Learn More About TPERestoring What Matters Most
Therapeutic apheresis offers a path forward for patients navigating complex and often resistant conditions.
Alzheimer's & Cognitive Decline
The landmark AMBAR trial demonstrated TPE slows Alzheimer's progression by 52–71% — with a superior safety profile to monoclonal antibodies.
Longevity & Health Optimization
Measurably reduce biological age and optimize healthspan through evidence-based plasma exchange, validated across 35 epigenetic clocks.
Autoimmune Disorders
Remove the pathogenic antibodies and inflammatory mediators driving conditions like myasthenia gravis, Guillain-Barré syndrome, and multiple sclerosis.
Post-Infectious Syndromes
Address the persistent inflammatory burden underlying Long COVID, PANDAS, and other chronic post-infectious conditions.
Not sure if apheresis is right for you? We offer complimentary discovery calls to discuss your condition.
Book a Free Discovery CallUnmatched Expertise. Unwavering Care.
At Global Apheresis, you are treated by the physicians who have defined this field — not technicians following a protocol, but the experts who wrote it.
Dobri Kiprov, M.D., H.P.
Dr. Kiprov is the foremost pioneer of therapeutic plasma exchange in the United States. With over 40 years of clinical and research experience, he has shaped the very field he practices — from founding the American Society for Apheresis to publishing more than 100 peer-reviewed papers that define the standard of care.
Trained in clinical immunology at Harvard's Massachusetts General Hospital, Dr. Kiprov was the first physician in the country to earn the Hemapheresis Practitioner certification. He served two terms on the ASFA Board of Directors and received the society's Presidential Award for his pioneering contributions.
His landmark research includes the first clinical proof that therapeutic plasma exchange reduces biological age, the first published data on TPE for Long COVID, and a pivotal role in the AMBAR trial for Alzheimer's disease. He currently leads a partnership with the Buck Institute studying the multi-omic effects of plasma exchange.
Credentials & Distinctions
- Harvard/MGH Fellowship — Clinical Immunology
- ASFA Presidential Award Recipient
- 100+ Peer-Reviewed Publications
- 15,000+ Treatments Overseen
- First U.S. Hemapheresis Practitioner (ASCP)
Allen P. Green, M.D.
Dr. Green is a board-certified clinical pathologist and one of the most experienced apheresis practitioners of his generation. Having performed over 500 therapeutic plasma exchange procedures, he brings both technical precision and genuine warmth to every patient interaction.
After training at UT Southwestern Medical Center under Dr. Ravi Sarode — one of the nation's leading experts in apheresis and transfusion medicine — Dr. Green built and scaled a longevity-focused apheresis practice from the ground up, growing it to 50 TPE procedures per month within its first year.
A veteran of the United States Air Force, Dr. Green now leads Global Apheresis's affiliate partnerships, training and certifying physicians nationwide to deliver the same quality of care that defines our Mill Valley practice.
Credentials & Distinctions
- Board-Certified Clinical Pathologist
- UT Southwestern — Residency Training
- 500+ TPE Procedures Performed
- U.S. Air Force Veteran
- American Society for Apheresis (ASFA) Member
Four Decades of Breakthrough Research
Our clinical protocols are not experimental — they are the product of the most extensive body of research in the history of therapeutic apheresis, led by the physician who built the field.
The Early Research.
Dr. Kiprov publishes his first major works on therapeutic apheresis, including contributions to the New England Journal of Medicine, helping define the clinical foundations of the field.
Parabiosis Research
Building on decades of lab research showing tissue rejuvenation through blood factor exchange, Dr. Kiprov begins translating these findings to human clinical practice.
The AMBAR Trial
The landmark AMBAR study demonstrates that therapeutic plasma exchange with albumin replacement slows Alzheimer's disease progression by 52–71% in moderate patients.
Biological Age Reduction
Dr. Kiprov publishes the first clinical proof that TPE reduces biological age by 1–3 years, measured through epigenetic clock analysis — a turning point for longevity medicine.
Buck Institute Partnership
Global Apheresis partners with the Buck Institute for Research on Aging in a placebo-controlled study analyzing multi-omic biomarkers and the systemic effects of plasma exchange.
Bring Apheresis to Your Practice
Global Apheresis offers a turnkey affiliate program for physicians and medical practices seeking to add therapeutic plasma exchange to their service offerings. We have designed a comprehensive partnership model that removes the complexity of launching an apheresis program from scratch.
Our affiliate partners benefit from the collective expertise of a team that has performed thousands of procedures, published extensively, and trained dozens of physicians across the country. You focus on patients. We handle the rest.
Complete Clinical Training
Physicians receive hands-on certification from Dr. Kiprov and Dr. Green — the same protocols, safety standards, and clinical excellence that define our Mill Valley practice.
Operational Blueprint
From equipment selection and supplier relationships to staffing models and patient scheduling, we provide a turnkey operational framework built on years of real-world optimization.
Ongoing Medical Direction
Our physicians serve as medical directors for affiliate locations, providing clinical oversight, patient vetting, and protocol guidance so you are never practicing in isolation.
Research & Credibility
Affiliate partners gain access to our research network, published protocols, and the credibility of the Global Apheresis name — backed by 100+ publications and four decades of clinical proof.
Your Path to Better Health
Starts Here
We understand that exploring treatment options for complex conditions can feel overwhelming. Our team is here to listen, answer your questions, and help you determine whether therapeutic apheresis is the right choice for you or someone you love.
Every discovery call is complimentary and completely confidential.
Mill Valley, CA 94941
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